Long title:
Oxygen in Paediatric Intensive Care (Oxy-PICU): A Randomised Multiple Centre Trial of Conservative versus Liberal Oxygenation Targets in Critically Ill Children
Short title:
Oxy-PICU
Chief Investigator:
Mark Peters
Organisation:
Great Ormond Street Hospital for Children NHS Foundation Trust
Funder:
National Institute for Health and Care Research (NIHR) – Health Technology Assessment (HTA) Programme
Lay Summary:
The optimal target for systemic oxygenation in critically ill children is unknown. Liberal oxygenation is widely practiced, but has been associated with harm in paediatric patients. We aimed to evaluate whether conservative oxygenation would reduce duration of organ support or incidence of death compared to standard care.
Project Website:
https://www.icnarc.org/research-studies/oxy-picu/
Associated Publications:
https://www.thelancet.com/article/S0140-6736(23)01968-2/fulltext